Article

Re-evaluation of SNP heritability in complex human traits

2016-09-09

Abstract excerpt

SNP heritability, the proportion of phenotypic variance explained by SNPs, has been reported for many hundreds of traits. Its estimation requires strong prior assumptions about the distribution of heritability across the genome, but the assumptions in current use have not been thoroughly tested. By analyzing imputed data for a large number of human traits, we empirically derive a model that more accurately describ...

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Literature Corpus work: 399fd876-153d-5afe-a482-c98f681b36a4
DOI: 10.1101/074310

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