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Article

Concepts, estimation and interpretation of SNP-based heritability.

Nature genetics - 30 Aug 2017

Yang Jian, Zeng Jian, Goddard Michael E, Wray Naomi R, Visscher Peter M

Abstract excerpt

Narrow-sense heritability (h2) is an important genetic parameter that quantifies the proportion of phenotypic variance in a trait attributable to the additive genetic variation generated by all causal variants. Estimation of h2 previously relied on closely related individuals, but recent developments allow estimation of the variance explained by all SNPs used in a genome-wide association study (GWAS) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28854176
DOI: 10.1038/ng.3941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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