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Article

Association between LAG3/CD4 gene variants and risk of Parkinson's disease.

European journal of clinical investigation - 1 Nov 2022

García-Martín Elena, Pastor Pau, Gómez-Tabales Javier, Alonso-Navarro Hortensia, Alvarez Ignacio, Buongiorno Mariateresa, Cerezo-Arias Maria de Las Olas, Aguilar Miquel, Agúndez José A G, Jiménez-Jiménez Félix Javier

Abstract excerpt

BACKGROUND/OBJECTIVES: Several recent studies suggest a possible role of lymphocyte activation 3 (LAG3) protein. LAG3 can behave as an α-synuclein ligand, and serum and cerebrospinal fluid-soluble LAG3 levels have been proposed as a marker of Parkinson's disease (PD). In this study, we aimed to investigate whether there is an association between 3 common single-nucleotide variations (SNVs) in the LAG3 gene and...

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Share to alpha-Synuclein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36224715
DOI: 10.1111/eci.13847
PMCID: PMC9787747

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