Article

Modeling and Simulation of CAR T cell Therapy in Chronic Lymphocytic Leukemia Patients

2022-12-01

Abstract excerpt

Advances in genetic engineering have made it possible to reprogram an individual’s immune cells to express receptors that recognize markers on tumor cell surfaces. The process of re-engineering T cell lymphocytes to express Chimeric Antigen Receptors (CARs) and reinfusing the CAR-modified T cells into patients to treat various cancers is being explored in clinical trials. While the majority of patients with some c...

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Literature Corpus work: 3987201f-52c8-5239-b836-70b85a504f33
DOI: 10.1101/2022.12.01.22282976

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