Article

Three-Compartment Model of CAR T-cell Immunotherapy

2019-09-24

Abstract excerpt

Immunotherapy has gained great momentum with chimeric antigen receptor T-cell (CAR T) therapy, in which patient’s T lymphocytes are genetically manipulated to recognize tumor-specific antigens to increase tumor elimination efficiency. Improved CAR T cell immunotherapy requires a better understanding of the interplay between CAR T cell doses and tumor burden, administration protocol, toxicity, resistance to immunot...

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Literature Corpus work: 1033c17c-6235-53fb-bfe1-da799db27d7f
DOI: 10.1101/779793

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