Article
CARTmath - A Mathematical Model of CAR-T Immunotherapy in Preclinical Models
2021-03-25
Abstract excerpt
Immunotherapy has gained great momentum with chimeric antigen receptor T cell (CAR-T) therapy, in which patient’s T lymphocytes are genetically manipulated to recognize tumor-specific antigens increasing tumor elimination efficiency. In the last years, CAR-T cell immunotherapy for hematological malignancies achieved a great response rate on patients and is a very promising therapy for several other malignanc...
Topics
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- Biosimilars and Bioanalytical Methods
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- vaccines and immunoinformatics approaches
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- aa00cab8-8baa-5529-8d7d-38824db091e8
- DOI
- 10.20944/preprints202103.0625.v1
