Article

Toxicity Management in CAR T cell therapy for B-ALL: Mathematical modelling as a new avenue for improvement

2016-04-22

Abstract excerpt

Advances in genetic engineering have made it possible to reprogram individual immune cells to express receptors that recognise markers on tumour cell surfaces. The process of re-engineering T cell lymphocytes to express Chimeric Antigen Receptors (CARs), and then re-infusing the CAR-modified T cells into patients to treat various cancers is referred to as CAR T cell therapy. This therapy is being explored in clin...

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Literature Corpus work: 628aa109-b24b-5c82-84be-56f7da98547d
DOI: 10.1101/049908

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