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Mitochondrial Transfer Triggered by TSLP Promotes Epithelial-Mesenchymal Transition in Human Lung Epithelial Cells Exposed to House Dust Mite

2025-12-04

Abstract excerpt

<title>Abstract</title> <p>Background Airway remodeling is a key pathological feature of asthma, closely linked to lung function decline and disease severity. Persistent inflammation, EMT, and mitochondrial dysfunction all contribute to this process. Although HDM strongly induces epithelial alarmins such as TSLP, how cytokine priming cooperates with subsequent allergen exposure to alter mitochondrial function and...

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Literature Corpus work
393a92d6-602b-560d-946a-c08d257233ef
DOI
10.21203/rs.3.rs-8162140/v1
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Mitochondrial Transfer Triggered by TSLP Promotes Epithelial-Mesenchymal Transition in Human Lung Epithelial Cells Exposed to House Dust MiteDOI 10.21203/rs.3.rs-8162140/v1
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