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Article

House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium.

American journal of respiratory cell and molecular biology - 1 Jan 2010

Heijink Irene H, Postma Dirkje S, Noordhoek Jacobien A, Broekema Martine, Kapus Andras

Abstract excerpt

The molecular basis of airway remodeling and loss of epithelial integrity in asthma is still undefined. We aimed to establish if exposure of human bronchial epithelium (16HBE cells) to asthma-related stimuli can induce epithelial-to-mesenchymal transition (EMT), a key process in tissue repair and remodeling associated with loss of intercellular contacts. We studied the effects of fibrogenic cytokine TGF-beta and...

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Source

Identifiers

PMID: 19372245
DOI: 10.1165/rcmb.2008-0449OC

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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