Article

CD127 imprints functional heterogeneity to diversify monocyte responses in human inflammatory diseases

2020-11-10

Abstract excerpt

Studies on human monocytes historically focused on characterization of bulk responses, whereas functional heterogeneity is largely unknown. Here, we identified an inducible population of CD127-expressing human monocytes under inflammatory conditions and named the subset M127. M127 is nearly absent in healthy individuals yet abundantly present in patients with infectious and inflammatory conditions such as COVID-19...

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Literature Corpus work: d2b68791-bfa8-5631-84ae-9ddd554a946c
DOI: 10.1101/2020.11.10.376277

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