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Article

Comprehensive single‐cell profiling of monocytes in HLA‐B27‐positive ankylosing spondylitis with acute anterior uveitis

28 Oct 2024

Abstract excerpt

Abstract Acute anterior uveitis (AAU) is a common extra‐articular manifestation of ankylosing spondylitis (AS), particularly in patients positive for the human leucocyte antigen (HLA)‐B27 genetic marker. To explore the underlying mechanisms of HLA‐B27+ AS‐associated AAU, we employed single‐cell RNA sequencing to profile the transcriptomes of peripheral blood mononuclear cells in three HLA‐B27+ AS‐associated AAU...

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Ocular Diseases and Behçet’s Syndrome
Spondyloarthritis Studies and Treatments
Systemic Lupus Erythematosus Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39473904
DOI: 10.1002/mco2.759

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