Article

Crystal structure and nanobodies against domain 3 of the malaria parasite fusogen <i>Plasmodium falciparum</i> HAP2

2025-12-02

Abstract excerpt

Malaria parasites are transmitted to humans through a bite from an infected female Anopheles mosquito. Within the mosquito midgut, malaria parasite gametes are activated and undergo fertilisation. If parasite fertilisation is perturbed, this stops the transmission of malaria parasites from mosquito to human. One proposed target of transmission-blocking interventions is Plasmodium falciparum fusogen PfHAP2, which...

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Literature Corpus work: 38a0b773-eb46-5cee-962b-0a3aada0eae4
DOI: 10.64898/2025.12.01.691709

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