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Article

Structure-guided design of a <i>Plasmodium vivax</i> Duffy binding protein-based vaccine immunogen

2024-06-26

Abstract excerpt

Plasmodium vivax remains one of the major causative agents of human malaria and a vaccine is urgently required. It is an obligate intracellular parasites and replication within red blood cells is essential for development of disease and for transmission. The interaction between PvDBP on the parasite surface and the DARC receptor on human reticulocytes is essential for a Plasmodium vivax blood stage infection. Hum...

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Identifiers and source

Literature Corpus work
eb590677-6203-57d4-8211-d552e5e3fc1c
DOI
10.1101/2024.06.23.600241
Open publication

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Structure-guided design of a <i>Plasmodium vivax</i> Duffy binding protein-based vaccine immunogenDOI 10.1101/2024.06.23.600241
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