Article

Structural elucidation of full-length Pfs48/45 in complex with potent mAbs isolated from a naturally exposed individual

2023-11-30

Abstract excerpt

<title>Abstract</title> Biomedical interventions capable of preventing the transmission of malaria-causing <italic>Plasmodium falciparum </italic>(Pf) between the human host and mosquito vector could prove a valuable tool in malaria elimination efforts. Pfs48/45, a gamete-surface protein essential for Pf development in the mosquito midgut, is a key component of clinical-stage transmission-blocking vaccines. An...

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Literature Corpus work: 941686c5-970a-5576-9d44-a73424e7bcb8
DOI: 10.21203/rs.3.rs-3605634/v1

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