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Myeloid malignancies and the microenvironment

16 Nov 2016

Abstract excerpt

Research in the last few years has revealed a sophisticated interaction network between multiple bone marrow cells that regulate different hematopoietic stem cell (HSC) properties such as proliferation, differentiation, localization, and self-renewal during homeostasis. These mechanisms are essential to keep the physiological HSC numbers in check and interfere with malignant progression. In addition to the...

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PMID: 28064238
DOI: 10.1182/blood-2016-09-670224

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