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Genome-wide screens in accelerated human stem cell-derived neural progenitor cells identify Zika virus host factors and drivers of proliferation

2018-11-22

Abstract excerpt

<h4>SUMMARY</h4> Neural progenitor cells (NPCs) are essential to brain development and their dysfunction is linked to several disorders, including autism, Zika Virus Congenital Syndrome, and cancer. Understanding of these conditions has been improved by advancements with stem cell-derived NPC models. However, current differentiation methods require many days or weeks to generate NPCs and show variability in effic...

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Literature Corpus work
e99e0f6a-a5be-592c-bfae-f706af5058ec
DOI
10.1101/476440
Open publication

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Genome-wide screens in accelerated human stem cell-derived neural progenitor cells identify Zika virus host factors and drivers of proliferationDOI 10.1101/476440
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