Article

Shank3 Modulates Sleep and Expression of Circadian Transcription Factors

2018-11-08

Abstract excerpt

Autism Spectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the United States and often co-presents with sleep problems. Sleep problems in ASD predict the severity of ASD core diagnostic symptoms and have a considerable impact on the quality of life of caregivers. Little is known, however, about the underlying molecular mechanisms. We investigated the role of Shank3 , a high confidence ASD...

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Literature Corpus work: 38247d3f-287b-558e-83ce-888b6630d5ac
DOI: 10.1101/465799

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