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Article

Shank3 modulates sleep and expression of circadian transcription factors

11 Apr 2019

Abstract excerpt

Autism Spectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the United States and often co-presents with sleep problems. Sleep problems in ASD predict the severity of ASD core diagnostic symptoms and have a considerable impact on the quality of life of caregivers. Little is known, however, about the underlying molecular mechanisms of sleep problems in ASD. We investigated the role of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30973326
DOI: 10.7554/elife.42819

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