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Article

Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications.

Journal of neurodevelopmental disorders - 16 Nov 2021

Delling Jan Philipp, Boeckers Tobias M

Abstract excerpt

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition, which is characterized by clinical heterogeneity and high heritability. Core symptoms of ASD include deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interests, or activities. Many genes have been identified that are associated with an increased risk for ASD. Proteins encoded by...

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Identifiers

PMID: 34784886
DOI: 10.1186/s11689-021-09397-8
PMCID: PMC8594088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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