Article

Kinetics Of Interferon-λ And Receptor Expression In Response To <i>In Vitro</i> Respiratory Viral Infection

2021-12-30

Abstract excerpt

The major protective immune response against viruses is production of type I and III interferons (IFNs). IFNs induce the expression of hundreds of IFN-stimulated genes (ISGs) that block viral replication and further viral spread. The ability of respiratory viruses to suppress induction of IFN-mediated antiviral defenses in infected epithelial cells may be a factor contributing to the particular pathogenicity of se...

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Literature Corpus work: 37cb5490-838c-51da-b2ce-397ed1cfb4fb
DOI: 10.1101/2021.12.30.474514

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