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HSV-1 infection induces a downstream shift of the +1 nucleosome

2024-03-11

Abstract excerpt

Herpes simplex virus 1 (HSV-1) infection induces a loss of host transcriptional activity and widespread disruption of host transcription termination, which leads to an induction of open chromatin downstream of genes. In this study, we show that lytic HSV-1 infection also leads to an extension of chromatin accessibility at promoters into downstream regions. This is most prominent for highly expressed genes and inde...

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Identifiers and source

Literature Corpus work
a881f9c4-e15b-553a-940c-b0e26f01d063
DOI
10.1101/2024.03.06.583707
Open publication

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HSV-1 infection induces a downstream shift of the +1 nucleosomeDOI 10.1101/2024.03.06.583707
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