Identification of herpes simplex virus RNAs that interact specifically with regulatory protein ICP27 in vivo.

doi:10.1074/jbc.M302063200

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Article

Identification of herpes simplex virus RNAs that interact specifically with regulatory protein ICP27 in vivo.

The Journal of biological chemistry - 29 Aug 2003

Sokolowski Marcus, Scott James E, Heaney Robert P, Patel Arvind H, Clements J Barklie

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) protein ICP27 has an essential regulatory role during viral replication, in part by post-transcriptional control of gene expression, and has a counterpart in all herpes viruses sequenced so far. Although much is known about the functions of this signature herpesvirus protein, little is known about its RNA binding capabilities; ICP27 interacts with specificity for a subset of...

Topics

Binding Sites
Blotting, Western
Gene Expression Regulation, Viral
Gene Library
Genome, Viral
Immediate-Early Proteins
Introns
Kinetics
Lac Operon
Models, Genetic
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmids

Protein Binding

Protein Structure, Tertiary

RNA

RNA, Messenger

RNA, Viral

Simplexvirus

Source

Open in PubMed

Identifiers

PMID: 12783881
DOI: 10.1074/jbc.M302063200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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