The Many Roles of the Highly Interactive HSV Protein ICP27, A Key Regulator of Infection

doi:10.2217/fmb.11.119

Article

The Many Roles of the Highly Interactive HSV Protein ICP27, A Key Regulator of Infection

1 Nov 2011

Abstract excerpt

Human herpes viruses cause an array of illnesses ranging from cancers for Epstein?Barr virus and Kaposi?s sarcoma-associated herpes virus, to painful skin lesions, and more rarely, keratitis and encephalitis for HSV. All herpes viruses encode a multifunctional protein, typified by HSV ICP27, which plays essential roles in viral infection. ICP27 functions in all stages of mRNA biogenesis from transcription, RNA...

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