Article

Transcriptome-wide association studies accounting for colocalization using Egger regression

2017-11-21

Abstract excerpt

Integrating genome-wide association (GWAS) and expression quantitative trait locus (eQTL) data into transcriptome-wide association studies (TWAS) based on predicted expression can boost power to detect novel disease loci or pinpoint the susceptibility gene at a known disease locus. However, it is often the case that multiple eQTL genes colocalize at disease loci, making the identification of the true susceptibilit...

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Literature Corpus work: 374baed9-ecad-5c49-8d55-d45f17b23453
DOI: 10.1101/223263

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