Article

A gene-level test for directional selection on gene expression

2022-11-04

Abstract excerpt

Most variants identified in human genome-wide association studies and scans for selection are non-coding. Interpretation of these variants’ effects and understanding of the way in which they contribute to phenotypic variation and adaptation in human populations is therefore limited by our understanding of gene regulation and by the difficulty in confidently linking non-coding variants to genes. To overcome this, w...

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Literature Corpus work: 37129e82-8c80-5d00-b420-54564efe7e95
DOI: 10.1101/2022.11.03.515083

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