Article

Functional partitioning of local and distal gene expression regulation in multiple human tissues

2016-03-31

Abstract excerpt

Studies of the genetics of gene expression have served as a key tool for linking genetic variants to phenotypes. Large-scale eQTL mapping studies have identified a large number of local eQTLs, but the molecular mechanism of how genetic variants regulate expression is still unclear, particularly for distal eQTLs, which these studies are not well-powered to detect. In this study, we use a heritability partitioning a...

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Literature Corpus work: f4e9fa02-d7f3-56bf-ba86-20e8114c314c
DOI: 10.1101/046383

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