Article

Anomaly pathway activities and transcriptome burden reveal cellular plasticity of human cancer

2023-04-28

Abstract excerpt

<h4>Background: </h4> It is now widely acknowledged that the adaptive evolutionary process of cancer cells is characterized by genomic and epigenetic alterations. Nevertheless, the extreme heterogeneity of cancer cells and the extreme sparsity of scRNA-seq data limited the understanding of cancer cell reconfiguration of anomaly pathway activity and adaptive evolution under selection pressure. <h4>Methods: </h4>:...

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Literature Corpus work: 36e1a2ed-4515-55d3-8fc6-2428f9d96ed3
DOI: 10.21203/rs.3.rs-2859072/v1

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