Article
RanBP2/Nup358 enhances miRNA activity by sumoylating and stabilizing Argonaute 1
2019-03-03
Abstract excerpt
<h4>SUMMARY</h4> RanBP2/Nup358 is one of the main components of the cytoplasmic filaments of the nuclear pore complex. It has been speculated that RanBP2, which has an E3 SUMO-ligase domain, may alter the composition of messenger ribonucleoprotein (mRNP) complexes as they emerge from the nuclear pore and thus regulate the ultimate fate of the mRNA in the cytoplasm. Four separate missense mutations in RanBP2 cause...
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Identifiers and source
- Literature Corpus work
- 36c6cb3b-a694-5903-af28-6b7ce920de0f
- DOI
- 10.1101/555896
