Article

The genetic driver of Acute Necrotizing Encephalopathy, <i>RANBP2</i> , regulates the inflammatory response to Influenza A virus infection

2025-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Influenza virus infections can cause severe complications such as Acute Necrotizing Encephalopathy (ANE), which is characterised by rapid onset pathological inflammation following febrile infection. Heterozygous dominant mutations in the nucleoporin RANBP2/Nup358 predispose to influenza-triggered ANE1. The aim of our study was to determine whether RANBP2 plays a role in IAV-triggered inflammator...

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Literature Corpus work: 73efd9eb-1dcb-5f9a-aed6-bb8c454413a4
DOI: 10.1101/2025.03.23.644734

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