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Article

Post-Transcriptional Regulation of Interferons and Their Signaling Pathways

4 Apr 2014

Abstract excerpt

Interferons (IFNs) are low molecular weight cell-derived proteins that include the type I, II, and III IFN families. IFNs are critical for an optimal immune response during microbial infections while dysregulated expression can lead to autoimmune diseases. Given its role in disease, it is important to understand cellular mechanisms of IFN regulation. 3' untranslated regions (3' UTRs) have emerged as potent...

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PMID: 24702117
DOI: 10.1089/jir.2013.0117

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