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Article

Immune dysregulation and RNA N6 ‐methyladenosine modification in sepsis

23 Sept 2022

Abstract excerpt

Sepsis is defined as life-threatening organ dysfunction caused by the host immune dysregulation to infection. It is a highly heterogeneous syndrome with complex pathophysiological mechanisms. The host immune response to sepsis can be divided into hyper-inflammatory and immune-suppressive phases which could exist simultaneously. In the initial stage, systemic immune response is activated after exposure to...

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PMID: 36149809
DOI: 10.1002/wrna.1764

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