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Article

A New Mouse Model of Diffuse Midline Glioma to Test Targeted Immunotherapies

2021-10-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Diffuse midline gliomas remain incurable, with consistently poor outcomes in children despite radiotherapy. Immunotherapeutic approaches hold promise, with the integration of the host’s immune system fundamental to their design. Here, we describe a new, genetically engineered immunocompetent model that incorporates interleukin 13 receptor alpha 2 (IL13Rα2), a tumor-associate...

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Literature Corpus work
36b62802-5dd4-583f-9e8c-a0260ce028f2
DOI
10.1101/2021.10.15.464284
Open publication

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A New Mouse Model of Diffuse Midline Glioma to Test Targeted ImmunotherapiesDOI 10.1101/2021.10.15.464284
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