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A new genetically engineered transplant model of glioma recapitulates key phenotypes of low- and high-grade gliomas

2025-10-31

Abstract excerpt

Immune competent animal models are essential in preclinical glioma research. The ability to investigate tumor development with key tumor microenvironment components such as immune infiltration, stromal cells and extracellular matrix allows for the investigation of these complex tumors. However, the current range of syngeneic models of glioma possess intrinsic limitations which must be acknowledged when designing a...

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Literature Corpus work
b7a730f8-7c82-5bfb-a7dd-a24dc7c33098
DOI
10.1101/2025.10.29.685449
Open publication

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A new genetically engineered transplant model of glioma recapitulates key phenotypes of low- and high-grade gliomasDOI 10.1101/2025.10.29.685449
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