Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vivo mouse models for adult brain tumors: Exploring tumorigenesis and advancing immunotherapy development

11 Jul 2024

Abstract excerpt

Brain tumors, particularly glioblastoma (GBM), are devastating and challenging to treat, with a low 5-year survival rate of only 6.6%. Mouse models are established to understand tumorigenesis and develop new therapeutic strategies. Large-scale genomic studies have facilitated the identification of genetic alterations driving human brain tumor development and progression. Genetically engineered mouse models...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Research and Treatments
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38990913
DOI: 10.1093/neuonc/noae131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vivo mouse models for adult brain tumors: Exploring tumorigenesis and advancing immunotherapy developmentPMID 38990913Read ↗

In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studiesSemantic proximity Read ↗

Mouse models of glioblastoma for the evaluation of novel therapeutic strategiesSemantic proximity Read ↗

Genetic modeling of gliomas in mice: new tools to tackle old problems.Semantic proximity Read ↗

Current trends in mouse models of glioblastomaSemantic proximity Read ↗

Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology ResearchSemantic proximity Read ↗

Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.Semantic proximity Read ↗

Contemporary Mouse Models in Glioma ResearchSemantic proximity Read ↗

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studiesSemantic proximity Read ↗

Molecular Pathogenesis of Malignant Glial TumorsSemantic proximity Read ↗

Genetically Engineered Mouse Models of Brain Cancer and the Promise of Preclinical TestingSemantic proximity Read ↗

Next-Generation in vivo Modeling of Human CancersSemantic proximity Read ↗

Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.