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CDSeqR: fast complete deconvolution for gene expression data from bulk tissues

24 May 2021

Abstract excerpt

BACKGROUND: Biological tissues consist of heterogenous populations of cells. Because gene expression patterns from bulk tissue samples reflect the contributions from all cells in the tissue, understanding the contribution of individual cell types to the overall gene expression in the tissue is fundamentally important. We recently developed a computational method, CDSeq, that can simultaneously estimate both...

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PMID: 34030626
DOI: 10.1186/s12859-021-04186-5

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