Article

KAT8 facilitates the proliferation of cancer cells through enhancing E7 function in HPV-associated cervical cancer

2024-12-26

Abstract excerpt

Persistent human papillomavirus (HPV) infection serves as the principal etiological factor in cervical cancer, with the oncoprotein E7, encoded by the virus, playing a key role in tumorigenesis. Despite this, targeted therapeutic strategies against E7 remain underexplored. KAT8, a lysine acetyltransferase, significantly contributes to oncogenesis through the regulation of transcription. However, its involvement in...

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Literature Corpus work: 36161670-f7dd-5a87-8e23-28eb5fa8d3ac
DOI: 10.1101/2024.12.26.629157

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