Article
Human Papillomavirus E6 and E7: The Cervical Cancer Hallmarks and Targets for Therapy
20 Jan 2020
Abstract excerpt
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women from the poorly/under-developed sectors of the world. It accounts for a high-mortality rate because of its late diagnosis and poor prognosis. Initial establishment and subsequent progression of this form of cancer are completely dependent on two major oncogenes E6 and E7, which are expressed constitutively leading to...
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