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Article

Human papillomavirus 16E6/E7 activates autophagy via Atg9B and LAMP1 in cervical cancer cells

18 Jun 2019

Abstract excerpt

BACKGROUNDS: Although the role of high-risk human papillomavirus (HPV) E6 and E7 in cellular malignant transformation has been elucidated， the function of both genes in cellular homeostasis is still unknown. Autophagy functions in maintenance of cellular homeostasis play a key role in the initiation and development of cancer and infectious disease. METHODS: Cervical cancer cell lines SiHa and CaSki were utilized...

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PMID: 31215164
DOI: 10.1002/cam4.2351

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