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Article

Genetic deletion of HPV E7 oncogene effectively eliminates HPV driven oropharyngeal cancer tumours

2022-06-22

Abstract excerpt

<title>Abstract</title> <p>The major HPV oncogenes E6 and E7 are known for its notoriety in driving the carcinogenic process in human papilloma virus (HPV) driven cancers. It is well-established that the removal of E7 dampens HPV cancer cell growth and proliferation. This has made E7 one of the most attractive targets for HPV cancers. Seminal work from our laboratory employed <italic>in vivo</italic> CRISPR editi...

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Literature Corpus work
ca99591e-d28d-5dcc-a2bb-94af691abeca
DOI
10.21203/rs.3.rs-1743660/v1
Open publication

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Genetic deletion of HPV E7 oncogene effectively eliminates HPV driven oropharyngeal cancer tumoursDOI 10.21203/rs.3.rs-1743660/v1
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