Article
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer
24 May 2024
Abstract excerpt
Human papillomaviruses (HPV) are a major cause of malignancy, contributing to ~5% of all human cancers worldwide, including most cervical cancer cases and a growing number of anogenital and oral cancers. The major HPV viral oncogenes, E6 and E7, manipulate many host cellular pathways that promote cell proliferation and survival, predisposing infected cells to malignant transformation. Despite the availability of...
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