Article

OrthologAL: A Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data

2024-11-26

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell and spatial transcriptomics provide unprecedented insight into the inner workings of disease. Pharmacotranscriptomic approaches are powerful tools that leverage gene expression data for drug repurposing and treatment discovery in many diseases. Multiple databases attempt to connect human cellular transcriptional responses to small molecules for use in transcriptome-based drug discove...

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Literature Corpus work: 36026fe1-c732-54ab-a926-fc7e8be77391
DOI: 10.1101/2024.11.25.625000

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