Article

Mutational load and the functional fraction of the human genome

2019-09-30

Abstract excerpt

The fraction of the human genome that is functional is a question of both evolutionary and practical importance. Studies of sequence divergence have suggested that the functional fraction of the human genome is likely to be no more than ∼15%. In contrast, the ENCODE project, a systematic effort to map regions of transcription, transcription factor association, chromatin structure, and histone modification, assigne...

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Literature Corpus work: 35f262aa-672b-5c16-90ad-97fa213161c4
DOI: 10.1101/785865

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