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Article

A Quantitative Genetic Model of Background Selection in Humans

2023-09-08

Abstract excerpt

Across the human genome, there are large-scale fluctuations in genetic diversity caused by the indirect effects of selection. This “linked selection signal” reflects the impact of selection according to the physical placement of functional regions and recombination rates along chromosomes. Previous work has shown that purifying selection acting against the steady influx of new deleterious mutations at functional p...

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Literature Corpus work
2c9150e1-885b-5b18-b4c5-2b4c40451677
DOI
10.1101/2023.09.07.556762
Open publication

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A Quantitative Genetic Model of Background Selection in HumansDOI 10.1101/2023.09.07.556762
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