Article

PfClpC Is An Essential Clp Chaperone Required For Plastid Integrity And Clp Protease Stability In <i>Plasmodium falciparum</i>

2016-10-12

Abstract excerpt

<h4>Summary</h4> The deadly malaria parasite, Plasmodium falciparum , contains a non-photosynthetic plastid known as the apicoplast, that functions to produce essential metabolites. Little is known about its biology or regulation, but drugs that target the apicoplast are clinically effective. Using phylogenetic analysis, we identified a putative complex of clp (caseinolytic protease) genes. We genetically target...

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Literature Corpus work: 1018bcbe-ba5c-5f7c-af2f-87cfef7daf04
DOI: 10.1101/080408

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