Article

Tumour cell-induced senescence-like state of macrophages plays a pivotal role in tumour stable growth after tumour cell emergence in immunocompetent condition

2022-11-09

Abstract excerpt

<h4>Background: </h4> The cancer stem cell theory proposes that tumour formation in vivo is driven only by specific tumour-initiating cells having stemness; however, clinical trials conducted to test drugs that target tumour stemness have provided unsatisfactory results thus far. Recent studies showed clear involvement of immunity in tumours; however, the requirements of tumour-initiation followed by stable growth...

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Literature Corpus work: 35a3e13d-506a-538c-a159-130d3b28eb95
DOI: 10.21203/rs.3.rs-2236823/v1

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