Article

Antigenic cancer persister cells survive direct T cell attack

2025-03-17

Abstract excerpt

<h4>Summary</h4> Drug-tolerant persister cancer cells were first reported fifteen years ago as a quiescent, reversible cell state which tolerates unattenuated cytotoxic drug stress. It remains unknown whether a similar phenomenon contributes to immune evasion. Here we report a persister state which survives weeks of direct cytotoxic T lymphocyte (CTL) attack. In contrast to previously known immune evasion mechani...

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Literature Corpus work: 2c0dcb74-afcd-59fb-90fc-141762187220
DOI: 10.1101/2025.03.14.643359

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