Article
Could senescence phenotypes strike the balance to promote tumor dormancy?
Cancer metastasis reviews - 1 Mar 2023
Chiu Fang-Yen, Kvadas Raegan M, Mheidly Zeinab, Shahbandi Ashkan, Jackson James G
Abstract excerpt
After treatment and surgery, patient tumors can initially respond followed by a rapid relapse, or respond well and seemingly be cured, but then recur years or decades later. The state of surviving cancer cells during the long, undetected period is termed dormancy. By definition, the dormant tumor cells do not proliferate to create a mass that is detectable or symptomatic, but also never die. An intrinsic state...
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