Article

Adverse prognosis of GM-CSF expression in human cutaneous melanoma

2025-06-02

Abstract excerpt

Tumor-associated macrophages (TAMs) represent a major immune population within the tumor microenvironment, influencing cancer progression and immune responses. Our group previously identified a subset of pro-inflammatory TAMs associated with poor prognosis in human melanoma. GM-CSF, a myeloid-priming cytokine, exhibits context-dependent effects on tumor growth and, despite its clinical use, its role in human melan...

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Literature Corpus work: 353bd4aa-7649-5b76-952c-34928ec9a506
DOI: 10.1101/2025.05.30.656980

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