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Article

YIF1B Mutational Dysregulation Drives Cutaneous Melanoma Progression by Remodeling the TME.

Human mutation - 1 Jan 2026

Wang Xiaohan, Ding Yangxu, Cai Wenbo, Liu Chaowei, Shi Huijuan

Abstract excerpt

YIF1B, a transmembrane protein involved in intracellular trafficking and signaling, is dysregulated in multiple cancers, but its role in SKCM remains unclear. We integrated multiomics data from cutaneous melanoma cohorts, including gene expression, DNA methylation, and somatic mutation profiles. Using the similarity network fusion (SNF) algorithm, we performed molecular subtyping based on prognosis-associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 42253503
DOI: 10.1155/humu/8907583
PMCID: PMC13239320

Genes

YIF1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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