Article

Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse

2023-06-11

Abstract excerpt

<h4>Summary</h4> Mouse models have been used extensively to study human coronary artery disease (CAD) or atherosclerosis and to test therapeutic targets. However, whether mouse and human share similar genetic factors and pathogenic mechanisms of atherosclerosis has not been thoroughly investigated in a data-driven manner. We conducted a cross-species comparison study to better understand atherosclerosis pathogene...

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Literature Corpus work: 353757df-737a-5564-b9cf-17bc97614ac0
DOI: 10.1101/2023.06.08.544148

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